PLK1, A Potential Target for Cancer Therapy
نویسندگان
چکیده
منابع مشابه
PLK1, A Potential Target for Cancer Therapy
Polo-like kinase 1 (PLK1) plays an important role in the initiation, maintenance, and completion of mitosis. Dysfunction of PLK1 may promote cancerous transformation and drive its progression. PLK1 overexpression has been found in a variety of human cancers and was associated with poor prognoses in cancers. Many studies have showed that inhibition of PLK1 could lead to death of cancer cells by ...
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ژورنال
عنوان ژورنال: Translational Oncology
سال: 2017
ISSN: 1936-5233
DOI: 10.1016/j.tranon.2016.10.003